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Relapsing polychondritis (RPC) is a rare autoimmune disease causing episodic inflammation and destruction of cartilaginous structures including ears, nose, trachea, larynx, and joints, with anti-type II collagen and anti-matrilin-1 antibodies. RPC is driven by Th1/Th17 immune attack on cartilage proteoglycans, complement activation, and neutrophil infiltration. Sea moss fucoidan has anti-inflammatory properties modulating cartilage-destructive MMPs and inflammatory cytokines; selenium supports chondrocyte GPx antioxidant protection; zinc supports collagen synthesis and cartilage matrix repair; magnesium supports connective tissue integrity. Corticosteroids and DMARDs (dapsone, methotrexate, biologics) are standard; sea moss provides cartilage-supportive nutritional support alongside specialist care.
