Sea Moss for Psoriatic Arthritis: IL-17, IL-23, TNF-alpha, Dactylitis, Enthesitis & Nail Psoriasis

Psoriatic arthritis (PsA) — seronegative inflammatory arthritis in ~30% of psoriasis patients; IL-17A/IL-23 axis (central: IL-23 → Th17/ILC3 → IL-17A/F → keratinocyte activation, synovial inflammation, bone erosion); TNF-alpha (synovial pannus, osteoclastogenesis); NF-kB (IL-1beta, IL-6, IL-8 cascade); HLA-B*27, -B*38, -B*39, -Cw*6 (psoriasis); PSORS1 locus; dactylitis (sausage digit — hallmark, tendon sheath/synovium); enthesitis (peritendinous insertion); nail psoriasis (onycholysis, pitting, nail matrix involvement); CASPAR criteria (classification); secukinumab/ixekizumab (IL-17A first-line); ustekinumab (IL-12/23); guselkumab/risankizumab (IL-23 specific); JAK inhibitors (tofacitinib, upadacitinib). Sea moss fucoidan NF-kB/IL-17/TNF-alpha synovial; selenium GPx joint; zinc metalloenzyme skin-joint; omega-3 EPA resolvin D1 synovial cartilage; iodine thyroid-skin axis. Full guide inside.

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Holistic Vitalis Irish Sea Moss delivers 92 essential minerals including selenium, zinc, and iodine — supporting immune balance and cellular resilience. Free shipping on orders $65+.

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