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Primary sclerosing cholangitis (PSC) causes progressive 'onion-skin' fibrosis of bile ducts through pANCA (65%), anti-GP2, and anti-beta-tubulin autoantibodies. NF-kB/TNF-alpha/IL-17/IL-23/TGF-beta Th17 inflammation drives cholestasis, cirrhosis, and CCA risk. IBD overlap (75% with UC), HLA-B8/DR3/DQ2. Sea moss fucoidan targets TGF-beta anti-fibrotic signaling; selenium supports hepatic selenoprotein P/GPx; omega-3 resolvin D1 reduces biliary inflammation; zinc supports liver metallothionein. Full mechanistic guide inside.
Holistic Vitalis Irish Sea Moss delivers 92 essential minerals including selenium, zinc, and iodine — supporting immune balance and cellular resilience. Free shipping on orders $65+.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
