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Osteoarthritis affects 32.5 million Americans as the most common form of arthritis, characterized by progressive cartilage degradation. Sea moss fucoidan inhibits MMP-13 (collagenase-3), the primary enzyme degrading type II collagen in articular cartilage. Sea moss provides copper and zinc required by lysyl oxidase for collagen crosslinking, and sulfated polysaccharides structurally analogous to chondroitin sulfate that support synovial fluid viscosity. Sea moss magnesium modulates pain sensitization. NSAIDs, physical therapy, and weight management are first-line; sea moss provides cartilage-protective nutritional support between flares.
