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Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease characterized by interface hepatitis (periportal lymphoplasmacytic infiltration with hepatocyte rosetting — hallmark biopsy finding); AIH-1 (anti-SMA/ASMA anti-smooth muscle actin, anti-F-actin, ANA — most common, adults); AIH-2 (anti-LKM1 anti-liver kidney microsomal antibody = anti-CYP2D6 — children, young adults, severe); anti-SLA/LP (anti-soluble liver antigen — most specific for AIH, also anti-liver pancreas); HLA-DR3 (severe, young, high relapse) + HLA-DR4 (milder, older); CD4+ Th1/Tfh → autoreactive B cells + CD8+ cytotoxic T cells → hepatocyte apoptosis → ALT/AST elevation → fibrosis/cirrhosis; simplified Besnier criteria; IAIHG score; prednisone + azathioprine (first-line — remission 80%); mycophenolate (AZA-intolerant); cyclosporine (children, refractory); budesonide (AIH without cirrhosis, reduced SE); tacrolimus; rituximab; liver transplant (decompensated). Sea moss fucoidan NF-kB/IL-6/TGF-beta hepatic; selenium hepatic GPx selenoprotein P; omega-3 resolvin D1 hepatic anti-fibrotic; zinc hepatic metalloenzyme FOXP3 Treg. Full guide inside.
Holistic Vitalis Irish Sea Moss delivers 92 essential minerals including selenium, zinc, and iodine — supporting immune balance and cellular resilience. Free shipping on orders $65+.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
