Alzheimer's disease affects 55 million people globally and is driven by amyloid-beta plaque accumulation, tau protein tangles, neuroinflammation, and cholinergic dysfunction. Sea moss fucoidan crosses the blood-brain barrier and inhibits BACE1 (the enzyme that generates amyloid-beta); selenium reduces oxidative stress in hippocampal neurons; iodine supports thyroid function critical for neurogenesis. This guide covers gut-brain axis mechanisms, the association between seaweed consumption and lower dementia rates in Japanese centenarians, and important cautions around iodine dosing.

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